Professor and Chairman
George Lynn Cross Research Professor
PI/Director, Oklahoma Center for Microbial Pathogenesis and Immunity, CoBRE
Professor, Associate Vice President for Health Sciences Research
Pathogenic spirochetes, Lyme disease pathogenesis, host-parasite relationships.
Cellular and molecular biology of apicomplexan parasites. Areas of special interest include parasite motility, protein secretion, second messenger signaling, genetics, and pathogenesis.
Molecular Pathogenesis of Bacterial Ocular Infections
Neuroimmunology; Mucosal Immunology with an emphasis on the eye; herpes simplex virus type 1-induced lymphangiogenesis and encephalitis, vaccine development
The intersection of the immune and nervous systems during infection and tumorigenesis.
Molecular mimicry, Autoimmunity and Infection
Bacterial pathogenesis, innate immunity, antimicrobial resistance, membrane lipid remodeling, biochemistry of transmembrane proteins, bacterial glycerophospholipids.
Microbial genomics, bacterial iron transport, bacterial regulatory networks, microbial pathogenesis
Fungal pathogenesis, fungal genetics, signal transduction, antifungal therapy
Assistant Professor, Graduate Student Liaison
The major histocompatibility complex (MHC) class I and class II molecules.
Professor, Presbyterian Health Foundation Presidential Professor
NKT cells and regulation of humoral immune responses
Development of adaptive immunity, V(D)J recombination.
Structural biology and biochemistry of bacterial protein toxins
Fungal pathogenesis, drug resistance mechanism, and novel antimicrobial therapy development.
Cytokines, mucosal immunology, inflammation, infection, cancer, cell signaling
Department of Microbiology and Immunology
University of Oklahoma Health Sciences Center
940 Stanton L. Young Blvd., BMSB 1053
Oklahoma City, OK 73104