Primary Faculty

Danny N. Dhanasekaran, Ph.D.

Professor, Department of Cell Biology
Samuel Roberts Noble Foundation Endowed Chair in Cancer Research
Associate Director for Basic Research, Stephenson Cancer Center
Director, SCC-COBRE & Center for Basic Cancer Research


Education:

Ph.D., Biochemistry, Indian Institute of Science Bangalore, India
M.Sc., Molecular Biology, Madurai University, Madurai, India 
B.Sc., Chemistry, St. John's College, Palayamkottai, India 


Contact Information:

Phone: (405) 271-6850
Fax: (405) 271-2507

 

Email: Danny-Dhanasekaran@ouhsc.edu 

 

Mailing Address:

Stephenson Cancer Center, OUHSC
975 NE 10th Street 1417 BRC West
Oklahoma City, 73104


Selected Publications:

 

Ha JH, Ward JD, Radhakrishnan R, Jayaraman M, Song YS, Dhanasekaran DN. Lysophosphatidic acid stimulates epithelial to mesenchymal transition marker Slug/Snail2 in ovarian cancer cells via Gαi2, Src, and HIF1α signaling nexus. Oncotarget. 2016; 7: 37664-37679. PMID: 27166196

 

Ha JH, Yan M, Gomathinayagam R, Jayaraman M, Husain S, Liu J, Mukherjee P, Reddy EP, Song YS, Dhanasekaran DN. Aberrant expression of JNK-associated leucine-zipper protein, JLP, promotes accelerated growth of ovarian cancer. Oncotarget. 2016; 7: 72845-72859. PMID: 27655714.

 

Ferraresi A, Titone R, Follo C, Castiglioni A, Chiorino G, Dhanasekaran DN, Isidoro C. The protein restriction mimetic Resveratrol is an autophagy inducer stronger than amino acid starvation in ovarian cancer cells. Mol Carcinog. 2017; 56: 2681-2691. PMID: 28856729

 

Chakraborty PK, Mustafi SB, Xiong X, Dwivedi SKD, Nesin V, Saha S, Zhang M, Dhanasekaran D, Jayaraman M, Mannel R, Moore K, McMeekin S, Yang D, Zuna R, Ding K, Tsiokas L, Bhattacharya R, Mukherjee P. MICU1 drives glycolysis and chemoresistance in ovarian cancer. Nat Commun. 2017; 8: 14634. PMID: 28530221

 

Jayaraman M, Radhakrishnan R, Mathews, CA, Yan M, Husain S, Moxley KM, Song YS, Dhanasekaran DN. Identification of novel diagnostic and prognostic miRNA signatures in endometrial cancer. Genes Cancer. 2017; 8: 566-576. PMID: 28740575

 

Dhanasekaran, DN, Reddy, EP. JNK-signaling: A multiplexing hub in programmed cell death. Genes Cancer. 2017; 8: 682-694. PMID: 29234486

 

Ha JH, Radhakrishnan R, Jayaraman M, Yan M, Ward JD, Fung KM, Moxley KM, Sood AK, Isidoro C, Mukherjee P, Song YS, Dhanasekaran DN. Lysophosphatidic Acid Induces Metabolic Reprogramming in Ovarian Cancer via a Pseudohypoxic Response. Cancer Res. 2018; doi: 10.1158/0008-5472. CAN-17-1624. [Epub ahead of print]. PMID: 29386184

 

 

Complete list of publications:

http://www.ncbi.nlm.nih.gov/sites/myncbi/danny.dhanasekaran.1/bibliography/41143600/public/?sort=date&direction=ascending

 

 

Profile last updated: July 24, 2019